Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection

Abstract

The pregnant cow urine (PCU) is an active sourceof antimicrobial agents that is used for fabricating chitosancoated Ag/AgCl nanoparticles (NPs) in the present study.These PCU@C-Ag/AgCl NPs were physicochemically char-acterized and evaluated for antimicrobial activity againstselected respiratory tract infection (RTI) pathogens. Theabsorption band around 420 nm in UV-Visible spectrumindicated the presence of Ag NPs. The spherical shape ofNPs was observed using TEM. Also, the crystalline structurewas confirmed using the XRD pattern. The PCU@C-Ag/AgClNPs showed strong antimicrobial activity against all testedRTI pathogens. In addition, FESEM analysis showed mor-phological changes in RTI bacterial pathogens. Thereby,PCU@C-Ag/AgCl NPs may be used as an antimicrobial ma-terial to treat RTIs in near future at clinical level.