Synthesis and characterization of PCU@C-Ag/AgCl nanoparticles as an antimicrobial material for respiratory tract infection
Abstract
The pregnant cow urine (PCU) is an active sourceof antimicrobial agents that is used for fabricating chitosancoated Ag/AgCl nanoparticles (NPs) in the present study.These PCU@C-Ag/AgCl NPs were physicochemically char-acterized and evaluated for antimicrobial activity againstselected respiratory tract infection (RTI) pathogens. Theabsorption band around 420 nm in UV-Visible spectrumindicated the presence of Ag NPs. The spherical shape ofNPs was observed using TEM. Also, the crystalline structurewas confirmed using the XRD pattern. The PCU@C-Ag/AgClNPs showed strong antimicrobial activity against all testedRTI pathogens. In addition, FESEM analysis showed mor-phological changes in RTI bacterial pathogens. Thereby,PCU@C-Ag/AgCl NPs may be used as an antimicrobial ma-terial to treat RTIs in near future at clinical level.
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Copyright (c) 2021 Senthilkumar Palanisamy, Kalaivani Subramanian, Lerince Godrina Bennet, Janani Ambrose, Aganiya Gopalakrishnan, Sudhagar Babu, Ranjithkumar Rajamani, Niraj Kumar Jha, Soumya Pandit, Sachin Kumar Singh, Kamal Dua, Piyush Kumar Gupta
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