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    Lipid And Polymer Based Nano-Phytotherapeutics

    • Om M. Bagade
    • Priyanka E. Doke-Bagade
    • Siddhesh E. Doke
    • Krushna S. Wankhade


    Abstract

    The development of efficient drug delivery systems is pivotal in modern pharmacotherapy, aiming to enhance biological efficacy while minimizing the adverse effects of pharmaceutical agents. Recent focus has shifted towards lipid as well as polymer-containing nano-phytotherapeutics, amalgamating the benefits of natural and synthetic materials. Lipid-containing nanocarriers, like liposomes and lipid nanoparticles, are particularly suited for encapsulating hydrophobic phytochemicals, thereby augmenting their bioavailability and stability. Incorporating biodegradable polymers like chitosan and polyethylene glycol facilitates controlled release and target-specific delivery. Furthermore, the utilization of plant-derived phytochemicals offers reduced toxicity compared to synthetic drugs. This chapter outlines current research in this domain, emphasizing the synergistic potential of lipid-based nanocarriers and biocompatible polymers for phytochemical delivery. Strategies encompass formulation techniques, surface modifications, and targeted drug release mechanisms. The potential applications of these systems in treating diverse diseases, including cancer, cardiovascular disorders, and infectious diseases, are also discussed. Overall, lipid and polymer-based Nano-phytotherapeutics exhibit promise as adaptable and biocompatible drug delivery platforms, heralding benefits for efficient and targeted phytochemical delivery, potentially revolutionizing modern medicine. Further advancement in this field is anticipated to yield novel therapeutic solutions with enhanced clinical outcomes and reduced side effects.

    Keywords: Bioavailability Controlled release Lipid nanoparticles Nano-phytotherapeutics Phytochemicals
    Section

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    Lipid And Polymer Based Nano-Phytotherapeutics . (2023). Nanofabrication, 8. https://doi.org/10.37819/nanofab.8.1773
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