Nano-Phytotherapeutic Interventions Targeting Skin Diseases and Disorders

Scope:

Human skin is recognized as the frontline defensive barrier against the various pathogens that cause most human infectious diseases and disorders. Skin diseases and disorders are of various types and frequently occur as health problems upsetting all ages, from infants to the aging population. Maintaining the skin healthy and disease-free is crucial due to interaction with diverse environmental pathogens. Both males and females are affected with various skin diseases/disorders, including rashes, pathogenic infections (viral, bacterial, fungal, parasitic, and others), tumors, cancer, wounds (acute and chronic), acne, burns, trauma, insect bites, pigmentations, and others. The first line of antibiotics is majorly used as a conventional strategy for eradicating and managing skin diseases/disorders. Sometimes antimicrobial therapeutics are combined with anti-inflammatory, immunomodulators, antipyretics, and other classes of drugs, as per disease condition, to get efficient outcomes. However, these conventional strategies have been reported with various adverse effects, the majority cases of systemic toxicity, thus the emergence of natural phytotherapeutics has become a crucial and essential strategy for the effective management of various skin diseases/disorders. In addition, as compared to conventional therapeutics, phytotherapeutics-based treatment approaches are cost-effective. Although herbal drugs exhibit potential therapeutic effects against skin diseases/disorders, due to poor solubility, permeability, and poor bioavailability, their direct administration or application is limited. Thus, nanotechnology-based approaches can play a crucial role in overcoming these limitations. to overcome various limitations associated with herbal therapeutics. In the recent era, various nanocarriers such as liposomes, solid lipid nanoparticles, hydrogels, scaffolds, metallic nanoparticles, polymeric nanoparticles, nanomicelles, and others have been reported to show targeted delivery of herbal drugs for treating various skin diseases and disorders. Nanosized phytotherapeutics (nano-phytotherapeutic) can lead to various advantages over conventional therapeutics, such as negligible adverse effects, improved patient compliance and tolerance, and cost-effectiveness.

The theme will highlight and include scientific works including original research articles, reviews, and mini-reviews focusing on various nano-phytotherapeutic interventions targeting skin diseases and disorders.

Keywords:

Nano-phytotherapeutics synthesis approaches
Phytochemical screening and characterization
Hydrogels and scaffold-based nano-phytotherapeutics
Lipid and polymer-based nano-phytotherapeutics
Modified Nano-phytotherapeutic strategies
Cancer and benign tumors
Chronic infections
Wound healing and tissue engineering
In-vitro, Ex-vivo and In-vivo studies
Immunotherapy and photo-thermal therapy
Pharmacokinetic and biodistribution

Herbal remedies have shown excessive potential for effectively curing several types of skin diseases and disorders. In the current era, most of the population is moving towards the traditional herbal remedial approaches and thus, phytotherapeutic strategies are getting immense importance in healthcare systems with improved commercial usage. This special issue will give enormous information to researchers, scientists, and professionals working in the research domain: phytochemicals, nanomedicine, targeted transdermal delivery systems, skin infections, anticancer and antimicrobial phytotherapeutic approaches.

Guest Editors:

Dr. Sabya Sachi Das, School of Pharmaceutical and Population Health Informatics, DIT University, India. Email: Email: sabya2049@gmail.com. ORCID: 0000-0002-4042-8525

Dr. Kavindra Kumar Kesari, Department of Applied Physics, School of Science, Aalto University, Finland. Email: kavindra.kesari@aalto.fi; kavindra.kesari@helsinki.fi. ORCID: 0000-0003-3622-9555

Dr. Chander Prakash, Professor & Dean, Head of Division of Research and Development & School of Mechanical Engineering, Lovely Professional University, India. E-mail: chander.mechengg@gmail.com; chander.prakash@lpu.co.in; ORCID: 0000-0003-0856-9712

Useful links:

Editorial guidelines: https://eaapublishing.org/journals/index.php/nanofab/pages/view/authorguidlines

Submit to: https://mc04.manuscriptcentral.com/nanofab/