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    Deep Brain Stimulation for Ischemic Stroke Rehabilitation: from Rodents to Human

    • Ruxu Geng
    • Yuhe Wang
    • Renzhi Wang
    • Xinjie Bao


    Abstract

    Ischemic stroke survivors often suffer from severe disability and impaired quality of life, and the current treatments are inadequate. Deep brain stimulation (DBS) is a promising strategy to enhance recovery and alleviate symptoms, as it can modulate the electrical activity of neural circuits and facilitate neuroprotection and regeneration. In this review, we conducted a comprehensive literature search and summarized the chronic sequelae and mechanisms of ischemic stroke. Then we discuss the common targets and outcomes of DBS in preclinical and clinical studies, as well as the challenges and opportunities of DBS for ischemic stroke treatment.

    Keywords: DBS ischemic stroke dentate nucleus motor dysfunction post-stroke pain
    Section

    References

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    Geng, Ruxu, et al. “Deep Brain Stimulation for Ischemic Stroke Rehabilitation: From Rodents to Human”. Human Brain, vol. 2, no. 3, Jan. 2024, doi:10.37819/hb.3.1779.
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    DOI: https://doi.org/10.37819/hb.3.1779

    Published: 2024-01-10

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